Preventive/Aggravating Effects of Commonly Used Drugs on Breast Cancer Progression

¹Department of Biophysics, PGIMER, Chandigarh,India

^*Corresponding Author

Dr. Jasmeet Kaur

Assistant Professor

Department of Biophysics

PGIMER, Chandigarh

India

Phone: 91-172-2755293

Email: kaur.jasmeet@pgimer.edu.in

Abstract

Breast cancer is the most common form of cancer among women worldwide. In the past decade increased awareness of breast cancer risk and mammography screening has led to the earlier identification of more breast cancer cases. Breast cancer incidence in developed countries is higher, however relative mortality is greater in developing countries. Studies have highlighted sedentary lifestyle, obesity, hormonal replacement therapy, reproductive history and excessive alcohol intake along with genetic factors to effect breast cancer incidence and progression in women. With changing lifestyle, use for regularly prescribed drugs including antacids, cholesterol lowering drugs, NSAIDS/anti-inflammatory drugs, laxatives, antipyretic/analgesics has seen a hike. Recent studies have linked the use of regularly prescribed drugs to the prevention and aggravation of breast cancer symptoms. Therefore, in this review we present a list of commonly prescribed drugs in relation to their preventive and aggravating effect on breast cancer.

Keywords:Breast cancer, Prevention, Estrogen-receptor negative breast cancer, Estrogen-receptor positive breast cancer, Triple negative breast cancer

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