Haptoglobin Phenotypes and Association with Vascular Complications in Nigerian Type 2 Diabetes Patients

¹Department of Chemical Pathology,Osun State University, Osogbo, Osun State, Nigeria

²Department of Medical Laboratory Science,University of Benin, Benin, Edo State, Nigeria

^*Corresponding Author

O.O. Olaniyan

Department of Chemical pathology

Osun State University

Osogbo

Nigeria

Cell Phone: +2348034766014

Email:olacube2001@gmail.com

Abstract

Haptoglobin phenotypes were determined in 120 type 2 diabetes mellitus (including 60 diabetics with vascular complications and 60 diabetics without any vascular complications) and were compared to 50 apparently healthy individuals. A higher frequency of Hp 2 allele gene and Hp 2-2 phenotype was observed in diabetics and diabetics with vascular complications respectively. We found an association between Hp 2 allele in type 2 diabetes mellitus and Hp 2-2 phenotypes in diabetics with vascular complications. Hence, we conclude that screening diabetics for Hp 2-2 phenotypes would be an added advantage in patient focus management.

Keywords: Haptoglobin phenotypes, Type 2 Diabetes, Vascular complications, Nigerian

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